Painful ophthalmoplegia in a patient with a history of marginal zone lymphoma

Abstract A 73-year-old man with a history of marginal zone lymphoma was admitted to the emergency room for diplopia and ipsilateral headache.The Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) demonstrated intense and symmetrical hypermetabolism of the cavernous sinuses, sawgrass virtuoso sg500 complete sublijet sublimation printer kit and hypermetabolic lesions diffusely in the lymph nodes and bones.The diagnosis of high-grade relapse of lymphomatous disease was made.In this context, the homogenous and symmetric lesion valhalla axys of the cavernous sinuses, without any other encephalic or meningeal lesions, raised the hypothesis of a paraneoplastic origin.

A plausible paraneoplastic link between the neuro-ophthalmological lesion and the malignant disorder is IgG4-related disease, a condition that may be associated with lymphoma.As in our case, this diagnosis is often presumptive because histopathological confirmation is difficult to obtain.

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